FOXO3-mediated chemo-protection in high-stage neuroblastoma depends on wild-type TP53 and SESN3

Forkhead box O class transcription factors are homeostasis regulators that control cell death, longevity and therapy-resistance. In neuroblastoma (NB), nuclear FOXO3 correlates with stage M disease and poor prognosis. To analyze whether FOXO3 contributes to drug-resistance in this childhood cancer,...

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Detalhes bibliográficos
Publicado no:Oncogene
Main Authors: Rupp, M, Hagenbuchner, J, Rass, B, Fiegl, H, Kiechl-Kohlendorfer, U, Obexer, P, Ausserlechner, M J
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2017
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5671944/
https://ncbi.nlm.nih.gov/pubmed/28869600
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2017.288
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