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C10ORF10/DEPP-mediated ROS accumulation is a critical modulator of FOXO3-induced autophagy
BACKGROUND: Neuroblastoma is the most common solid tumor in childhood and develops from undifferentiated progenitor cells of the sympathetic nervous system. In neuronal tumor cells DNA-damaging chemotherapeutic agents activate the transcription factor FOXO3 which regulates the formation of reactive...
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| Publicado no: | Mol Cancer |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
BioMed Central
2017
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5445297/ https://ncbi.nlm.nih.gov/pubmed/28545464 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12943-017-0661-4 |
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