A balance between elongation and trimming regulates telomere stability in stem cells

by Rivera, Teresa, Haggblom, Candy, Cosconati, Sandro, Karlseder, Jan
Published in Nat Struct Mol Biol (2016)

Structure-Based Virtual Screening and Biological Evaluation of Mycobacterium tuberculosis Adenosine 5′-Phosphosulfate Reductase Inhibitors

by Cosconati, Sandro, Hong, Jiyoung A., Novellino, Ettore, Carroll, Kate S, Goodsell, David S., Olson, Arthur J
Published 2008

Virtual Screening with AutoDock: Theory and Practice

by Cosconati, Sandro, Forli, Stefano, Perryman, Alex L., Harris, Rodney, Goodsell, David S., Olson, Arthur J.
Published 2010

Olive Leaves and Hibiscus Flowers Extracts-Based Preparation Protect Brain from Oxidative Stress-Induced Injury

by Chiaino, Elda, Micucci, Matteo, Cosconati, Sandro, Novellino, Ettore, Budriesi, Roberta, Chiarini, Alberto, Frosini, Maria
Published in Antioxidants (Basel) (2020)

Synthesis and Gene Silencing Properties of siRNAs Containing Terminal Amide Linkages

by Gaglione, Maria, Mercurio, M. Emilia, Potenza, Nicoletta, Mosca, Nicola, Russo, Aniello, Novellino, Ettore, Cosconati, Sandro, Messere, Anna
Published 2014

Endogenous vs Exogenous Allosteric Modulators in GPCRs: A dispute for shuttling CB(1) among different membrane microenvironments

by Stornaiuolo, Mariano, Bruno, Agostino, Botta, Lorenzo, Regina, Giuseppe La, Cosconati, Sandro, Silvestri, Romano, Marinelli, Luciana, Novellino, Ettore
Published in Sci Rep (2015)

Identification of novel indole derivatives acting as inhibitors of the Keap1–Nrf2 interaction

by Cosimelli, Barbara, Greco, Giovanni, Laneri, Sonia, Novellino, Ettore, Sacchi, Antonia, Amendola, Giorgio, Cosconati, Sandro, Bortolozzi, Roberta, Viola, Giampietro
Published in J Enzyme Inhib Med Chem (2019)

Tuning RNA Interference by Enhancing siRNA/PAZ Recognition

by Gaglione, Maria, Potenza, Nicoletta, Di Fabio, Giovanni, Romanucci, Valeria, Mosca, Nicola, Russo, Aniello, Novellino, Ettore, Cosconati, Sandro, Messere, Anna
Published 2012

Sampling protein motion and solvent effect during ligand binding

by Limongelli, Vittorio, Marinelli, Luciana, Cosconati, Sandro, La Motta, Concettina, Sartini, Stefania, Mugnaini, Laura, Da Settimo, Federico, Novellino, Ettore, Parrinello, Michele
Published 2012

3-(Fur-2-yl)-10-(2-phenylethyl)-[1,2,4]triazino[4,3-a]benzimidazol-4(10H)-one, a Novel Adenosine Receptor Antagonist with A(2A)-Mediated Neuroprotective Effects

by Scatena, Alessia, Fornai, Francesco, Trincavelli, Maria Letizia, Taliani, Sabrina, Daniele, Simona, Pugliesi, Isabella, Cosconati, Sandro, Martini, Claudia, Da Settimo, Federico
Published 2011

Protein Flexibility in Virtual Screening: The BACE-1 Case Study

by Cosconati, Sandro, Marinelli, Luciana, Di Leva, Francesco Saverio, La Pietra, Valeria, De Simone, Angela, Mancini, Francesca, Andrisano, Vincenza, Novellino, Ettore, Goodsell, David S., Olson, Arthur J.
Published 2012

Studies on enantioselectivity of chiral 4-acetylamino-6-alkyloxy-2-alkylthiopyrimidines acting as antagonists of the human A(3) adenosine receptor

by Cosimelli, Barbara, Greco, Giovanni, Laneri, Sonia, Novellino, Ettore, Sacchi, Antonia, Collina, Simona, Rossi, Daniela, Cosconati, Sandro, Barresi, Elisabetta, Taliani, Sabrina, Trincavelli, Maria Letizia, Martini, Claudia
Published in Medchemcomm (2017)

Two novel SIRT1 activators, SCIC2 and SCIC2.1, enhance SIRT1-mediated effects in stress response and senescence

by Scisciola, Lucia, Sarno, Federica, Carafa, Vincenzo, Cosconati, Sandro, Di Maro, Salvatore, Ciuffreda, Loreta, De Angelis, Antonella, Stiuso, Paola, Feoli, Alessandra, Sbardella, Gianluca, Altucci, Lucia, Nebbioso, Angela
Published in Epigenetics (2020)

Decoration of chondroitin polysaccharide with threonine: synthesis, conformational study and ice-recrystallization inhibition activity

by Laezza, Antonio, Casillo, Angela, Cosconati, Sandro, Biggs, Caroline I., Fabozzi, Antonio, Paduano, Luigi, Iadonisi, Alfonso, Novellino, Ettore, Gibson, Matthew I., Randazzo, Antonio, Corsaro, Maria M., Bedini, Emiliano
Published in Biomacromolecules (2017)

Novel 2-substituted-benzimidazole-6-sulfonamides as carbonic anhydrase inhibitors: synthesis, biological evaluation against isoforms I, II, IX and XII and molecular docking studies

by Milite, Ciro, Amendola, Giorgio, Nocentini, Alessio, Bua, Silvia, Cipriano, Alessandra, Barresi, Elisabetta, Feoli, Alessandra, Novellino, Ettore, Da Settimo, Federico, Supuran, Claudiu T., Castellano, Sabrina, Cosconati, Sandro, Taliani, Sabrina
Published in J Enzyme Inhib Med Chem (2019)

Discovery of Pyrido[3′,2′:5,6]thiopyrano[4,3-d]pyrimidine-Based Antiproliferative Multikinase Inhibitors

by Salerno, Silvia, Barresi, Elisabetta, García-Argáez, Aída Nelly, Taliani, Sabrina, Simorini, Francesca, Amendola, Giorgio, Tomassi, Stefano, Cosconati, Sandro, Novellino, Ettore, Da Settimo, Federico, Marini, Anna Maria, Dalla Via, Lisa
Published in ACS Med Chem Lett (2019)

Discovery of a Novel Chemotype of Histone Lysine Methyltransferase EHMT1/2 (GLP/G9a) Inhibitors: Rational Design, Synthesis, Biological Evaluation, and Co-crystal Structure

by Milite, Ciro, Feoli, Alessandra, Horton, John R., Rescigno, Donatella, Cipriano, Alessandra, Pisapia, Vincenzo, Viviano, Monica, Pepe, Giacomo, Amendola, Giorgio, Novellino, Ettore, Cosconati, Sandro, Cheng, Xiaodong, Castellano, Sabrina, Sbardella, Gianluca
Published in J Med Chem (2019)

Structure-activity relationship of the exopolysaccharide from a psychrophilic bacterium: a strategy for cryoprotection

by Casillo, Angela, Parrilli, Ermenegilda, Sannino, Filomena, Mitchell, Daniel E., Gibson, Matthew I., Marino, Gennaro, Lanzetta, Rosa, Parrilli, Michelangelo, Cosconati, Sandro, Novellino, Ettore, Randazzo, Antonio, Tutino, Maria L., Corsaro, M. Michela
Published in Carbohydr Polym (2016)

Identification of Highly Conserved Residues Involved in Inhibition of HIV-1 RNase H Function by Diketo Acid Derivatives

by Corona, Angela, Di Leva, Francesco Saverio, Thierry, Sylvain, Pescatori, Luca, Cuzzucoli Crucitti, Giuliana, Subra, Frederic, Delelis, Olivier, Esposito, Francesca, Rigogliuso, Giuseppe, Costi, Roberta, Cosconati, Sandro, Novellino, Ettore, Di Santo, Roberto, Tramontano, Enzo
Published 2014

Antitumor efficacy of Kisspeptin in human malignant mesothelioma cells

by Ciaramella, Vincenza, Della Corte, Carminia Maria, Di Mauro, Concetta, Tomassi, Stefano, Di Maro, Salvatore, Troiani, Teresa, Martinelli, Erika, Bianco, Roberto, Cosconati, Sandro, Pierantoni, Riccardo, Meccariello, Rosaria, Chianese, Rosanna, Ciardiello, Fortunato, Morgillo, Floriana
Published in Oncotarget (2018)