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Ecdysteroid Derivatives that Reverse P-Glycoprotein-Mediated Drug Resistance

[Image: see text] The expression of multidrug resistance P-glycoprotein (P-gp) by cancer cells represents one of the major drawbacks to successful cancer therapy. Accordingly, the development of drugs that inhibit the activity of this transporter remains a major challenge in cancer drug discovery. I...

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Detalhes bibliográficos
Publicado no:J Nat Prod
Main Authors: Bortolozzi, Roberta, Luraghi, Andrea, Mattiuzzo, Elena, Sacchetti, Alessandro, Silvani, Alessandra, Viola, Giampietro
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society and American Society of Pharmacognosy 2020
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC8009596/
https://ncbi.nlm.nih.gov/pubmed/32790992
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jnatprod.0c00334
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