Importance of single molecular determinants in the fidelity of expanded genetic codes

The site-selective encoding of noncanonical amino acids (NAAs) is a powerful technique for the installation of novel chemical functional groups in proteins. This is often achieved by recoding a stop codon and requires two additional components: an evolved aminoacyl tRNA synthetase (AARS) and a cogna...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Antonczak, Alicja K., Simova, Zuzana, Yonemoto, Isaac T., Bochtler, Matthias, Piasecka, Anna, Czapińska, Honorata, Brancale, Andrea, Tippmann, Eric M.
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: National Academy of Sciences 2011
Gaiak:
Biological Sciences
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3029751/
https://ncbi.nlm.nih.gov/pubmed/21224416
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1012276108
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