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CpG underrepresentation and the bacterial CpG-specific DNA methyltransferase M.MpeI

Cytosine methylation promotes deamination. In eukaryotes, CpG methylation is thought to account for CpG underrepresentation. Whether scarcity of CpGs in prokaryotic genomes is diagnostic for methylation is not clear. Here, we report that Mycoplasms tend to be CpG depleted and to harbor a family of c...

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Autors principals: Wojciechowski, Marek, Czapinska, Honorata, Bochtler, Matthias
Format: Artigo
Idioma:Inglês
Publicat: National Academy of Sciences 2013
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538198/
https://ncbi.nlm.nih.gov/pubmed/23248272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207986110
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