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CpG underrepresentation and the bacterial CpG-specific DNA methyltransferase M.MpeI

Cytosine methylation promotes deamination. In eukaryotes, CpG methylation is thought to account for CpG underrepresentation. Whether scarcity of CpGs in prokaryotic genomes is diagnostic for methylation is not clear. Here, we report that Mycoplasms tend to be CpG depleted and to harbor a family of c...

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Detalhes bibliográficos
Main Authors: Wojciechowski, Marek, Czapinska, Honorata, Bochtler, Matthias
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2013
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538198/
https://ncbi.nlm.nih.gov/pubmed/23248272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207986110
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