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CpG underrepresentation and the bacterial CpG-specific DNA methyltransferase M.MpeI

Cytosine methylation promotes deamination. In eukaryotes, CpG methylation is thought to account for CpG underrepresentation. Whether scarcity of CpGs in prokaryotic genomes is diagnostic for methylation is not clear. Here, we report that Mycoplasms tend to be CpG depleted and to harbor a family of c...

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主要な著者: Wojciechowski, Marek, Czapinska, Honorata, Bochtler, Matthias
フォーマット: Artigo
言語:Inglês
出版事項: National Academy of Sciences 2013
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オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538198/
https://ncbi.nlm.nih.gov/pubmed/23248272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207986110
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