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CpG underrepresentation and the bacterial CpG-specific DNA methyltransferase M.MpeI

Cytosine methylation promotes deamination. In eukaryotes, CpG methylation is thought to account for CpG underrepresentation. Whether scarcity of CpGs in prokaryotic genomes is diagnostic for methylation is not clear. Here, we report that Mycoplasms tend to be CpG depleted and to harbor a family of c...

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Detaylı Bibliyografya
Asıl Yazarlar: Wojciechowski, Marek, Czapinska, Honorata, Bochtler, Matthias
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: National Academy of Sciences 2013
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538198/
https://ncbi.nlm.nih.gov/pubmed/23248272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1207986110
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