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Crystal structure of the ββα-Me type II restriction endonuclease Hpy99I with target DNA

The ββα-Me restriction endonuclease (REase) Hpy99I recognizes the CGWCG target sequence and cleaves it with unusual stagger (five nucleotide 5′-recessed ends). Here we present the crystal structure of the specific complex of the dimeric enzyme with DNA. The Hpy99I protomer consists of an antiparalle...

詳細記述

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書誌詳細
主要な著者: Sokolowska, Monika, Czapinska, Honorata, Bochtler, Matthias
フォーマット: Artigo
言語:Inglês
出版事項: Oxford University Press 2009
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC2699513/
https://ncbi.nlm.nih.gov/pubmed/19380375
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp228
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