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Crystal structure of the ββα-Me type II restriction endonuclease Hpy99I with target DNA
The ββα-Me restriction endonuclease (REase) Hpy99I recognizes the CGWCG target sequence and cleaves it with unusual stagger (five nucleotide 5′-recessed ends). Here we present the crystal structure of the specific complex of the dimeric enzyme with DNA. The Hpy99I protomer consists of an antiparalle...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Oxford University Press
2009
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2699513/ https://ncbi.nlm.nih.gov/pubmed/19380375 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkp228 |
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