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Crystal structure and mechanism of action of the N6-methyladenine-dependent type IIM restriction endonuclease R.DpnI

DNA methylation-dependent restriction enzymes have many applications in genetic engineering and in the analysis of the epigenetic state of eukaryotic genomes. Nevertheless, high-resolution structures have not yet been reported, and therefore mechanisms of DNA methylation-dependent cleavage are not u...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Siwek, Wojciech, Czapinska, Honorata, Bochtler, Matthias, Bujnicki, Janusz M., Skowronek, Krzysztof
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: Oxford University Press 2012
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3424567/
https://ncbi.nlm.nih.gov/pubmed/22610857
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gks428
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