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Characterization of the Mode of Action of a Potent Dengue Virus Capsid Inhibitor

Dengue viruses (DV) represent a significant global health burden, with up to 400 million infections every year and around 500,000 infected individuals developing life-threatening disease. In spite of attempts to develop vaccine candidates and antiviral drugs, there is a lack of approved therapeutics...

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Autori principali: Scaturro, Pietro, Trist, Iuni Margaret Laura, Paul, David, Kumar, Anil, Acosta, Eliana G., Byrd, Chelsea M., Jordan, Robert, Brancale, Andrea, Bartenschlager, Ralf
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2014
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC4178822/
https://ncbi.nlm.nih.gov/pubmed/25056895
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.01745-14
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