Potent Plasmablast-Derived Antibodies Elicited by the National Institutes of Health Dengue Vaccine

Exposure to dengue virus (DENV) is thought to elicit lifelong immunity, mediated by DENV-neutralizing antibodies (nAbs). However, Abs generated by primary infections confer serotype-specific protection, and immunity against other serotypes develops only after subsequent infections. Accordingly, the...

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Pubblicato in:J Virol
Autori principali: Magnani, Diogo M., Silveira, Cassia G. T., Ricciardi, Michael J., Gonzalez-Nieto, Lucas, Pedreño-Lopez, Núria, Bailey, Varian K., Gutman, Martin J., Maxwell, Helen S., Domingues, Aline, Costa, Priscilla R., Ferrari, Lilian, Goulart, Raphaella, Martins, Mauricio A., Martinez-Navio, José M., Fuchs, Sebastian P., Kalil, Jorge, Timenetsky, Maria do Carmo, Wrammert, Jens, Whitehead, Stephen S., Burton, Dennis R., Desrosiers, Ronald C., Kallas, Esper G., Watkins, David I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2017
Soggetti:
Vaccines and Antiviral Agents
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC5660501/
https://ncbi.nlm.nih.gov/pubmed/28878078
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00867-17
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