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A human inferred germline antibody binds to an immunodominant epitope and neutralizes Zika virus

The isolation of neutralizing monoclonal antibodies (nmAbs) against the Zika virus (ZIKV) might lead to novel preventative strategies for infections in at-risk individuals, primarily pregnant women. Here we describe the characterization of human mAbs from the plasmablasts of an acutely infected pati...

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Publicado no:PLoS Negl Trop Dis
Main Authors: Magnani, Diogo M., Silveira, Cassia G. T., Rosen, Brandon C., Ricciardi, Michael J., Pedreño-Lopez, Núria, Gutman, Martin J., Bailey, Varian K., Maxwell, Helen S., Domingues, Aline, Gonzalez-Nieto, Lucas, Avelino-Silva, Vivian I., Trindade, Mateus, Nogueira, Juliana, Oliveira, Consuelo S., Maestri, Alvino, Felix, Alvina Clara, Levi, José Eduardo, Nogueira, Mauricio L., Martins, Mauricio A., Martinez-Navio, José M., Fuchs, Sebastian P., Whitehead, Stephen S., Burton, Dennis R., Desrosiers, Ronald C., Kallas, Esper G., Watkins, David I.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5481143/
https://ncbi.nlm.nih.gov/pubmed/28604797
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0005655
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