Castanospermine, a Potent Inhibitor of Dengue Virus Infection In Vitro and In Vivo

Previous studies have suggested that α-glucosidase inhibitors such as castanospermine and deoxynojirimycin inhibit dengue virus type 1 infection by disrupting the folding of the structural proteins prM and E, a step crucial to viral secretion. We extend these studies by evaluating the inhibitory act...

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Главные авторы: Whitby, Kevin, Pierson, Theodore C., Geiss, Brian, Lane, Kelly, Engle, Michael, Zhou, Yi, Doms, Robert W., Diamond, Michael S.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2005
Предметы:
Vaccines and Antiviral Agents
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC1168722/
https://ncbi.nlm.nih.gov/pubmed/15994763
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.79.14.8698-8706.2005
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