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Impairment of cocaine-mediated behaviours in mice by clinically relevant Ras-ERK inhibitors
Ras-ERK signalling in the brain plays a central role in drug addiction. However, to date, no clinically relevant inhibitor of this cascade has been tested in experimental models of addiction, a necessary step toward clinical trials. We designed two new cell-penetrating peptides - RB1 and RB3 - that...
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| Publicado no: | eLife |
|---|---|
| Main Authors: | , , , , , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
eLife Sciences Publications, Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4996650/ https://ncbi.nlm.nih.gov/pubmed/27557444 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.7554/eLife.17111 |
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