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The Inhibition of RasGRF2, But Not RasGRF1, Alters Cocaine Reward in Mice

Ras/Raf/MEK/ERK (Ras-ERK) signaling has been implicated in the effects of drugs of abuse. Inhibitors of MEK1/2, the kinases upstream of ERK1/2, have been critical in defining the role of the Ras-ERK cascade in drug-dependent alterations in behavioral plasticity, but the Ras family of small GTPases h...

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Bibliografski detalji
Izdano u:J Neurosci
Glavni autori: Bernardi, Rick E., Olevska, Anastasia, Morella, Ilaria, Fasano, Stefania, Santos, Eugenio, Brambilla, Riccardo, Spanagel, Rainer
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2019
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6687905/
https://ncbi.nlm.nih.gov/pubmed/31182637
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1120-18.2019
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