A concise Diels–Alder strategy leading to congeners of the ABC ring system of the marine alkaloid ‘upenamide

av Wenzler, Marta E., Melancon, Bruce J., Sulikowski, Gary A.
I publikationen Tetrahedron Lett (2016)

The succinct synthesis of AT13387, a clinically relevant Hsp90 inhibitor

av Kaur, Jatinder, Bhardwaj, Atul, Melancon, Bruce J., Blagg, Brian S. J.
I publikationen Synth Commun (2019)

Microplate-Based Assay for Identifying Small Molecules That Bind a Specific Intersubunit Interface within the Assembled HIV-1 Capsid

av Halambage, Upul D., Wong, Jason P., Melancon, Bruce J., Lindsley, Craig W., Aiken, Christopher
I publikationen Antimicrob Agents Chemother (2015)

Allosteric modulation of the M(1) muscarinic acetylcholine receptor: improving cognition and a potential treatment for schizophrenia and Alzheimer′s disease

av Melancon, Bruce J., Tarr, James C., Panarese, Joseph D., Wood, Michael R., Lindsley, Craig W.
Publicerad 2013

Allosteric Modulation of 7 Transmembrane Spanning Receptors: Theory, Practice and Opportunities for CNS Drug Discovery()

av Melancon, Bruce J., Hopkins, Corey R., Wood, Michael R., Emmitte, Kyle A., Niswender, Colleen M., Christopoulos, Arthur, Conn, P. Jeffrey, Lindsley, Craig W.
Publicerad 2012

Light-Induced Isomerization of Apoptolidin A leads to Inversion of C2-C3 Double Bond Geometry

av Bachmann, Brian O., McNees, Ruth, Melancon, Bruce J., Ghidu, Victor P., Clark, Rachel, Crews, Brenda C., DeGuire, Sean M., Marnett, Lawrence J., Sulikowski, Gary A.
Publicerad 2010

Spirocyclic replacements for the isatin in the highly selective, muscarinic M(1) PAM ML137: the continued optimization of an MLPCN probe molecule

av Poslusney, Michael S., Melancon, Bruce J., Gentry, Patrick R., Sheffler, Douglas J., Bridges, Thomas M., Utley, Thomas J., Daniels, J. Scott, Niswender, Colleen M., Conn, P. Jeffrey, Lindsley, Craig W., Wood, Michael R.
Publicerad 2013

Novel M(4) positive allosteric modulators derived from questioning the role and impact of a presumed intramolecular hydrogen-bonding motif in β-amino carboxamide-harboring ligands

av Poslusney, Michael S., Salovich, James M., Wood, Michael R., Melancon, Bruce J., Bollinger, Katrina A., Luscombe, Vincent B., Rodriguez, Alice L., Engers, Darren W., Bridges, Thomas M., Niswender, Colleen M., Conn, P. Jeffrey, Lindsley, Craig W.
I publikationen Bioorg Med Chem Lett (2018)

A Structural Model for Binding of the Serine-Rich Repeat Adhesin GspB to Host Carbohydrate Receptors

av Pyburn, Tasia M., Bensing, Barbara A., Xiong, Yan Q., Melancon, Bruce J., Tomasiak, Thomas M., Ward, Nicholas J., Yankovskaya, Victoria, Oliver, Kevin M., Cecchini, Gary, Sulikowski, Gary A., Tyska, Matthew J., Sullam, Paul M., Iverson, T. M.
Publicerad 2011

Correction: A Structural Model for Binding of the Serine-Rich Repeat Adhesin GspB to Host Carbohydrate Receptors

av Pyburn, Tasia M., Bensing, Barbara A., Xiong, Yan Q., Melancon, Bruce J., Tomasiak, Thomas M., Ward, Nicholas J., Yankovskaya, Victoria, Oliver, Kevin M., Cecchini, Gary, Sulikowski, Gary A., Tyska, Matthew J., Sullam, Paul M., Iverson, T. M.
Publicerad 2012

Chromophore Formation in Resorcinarene Solutions and the Visual Detection of Mono- and Oligosaccharides

av He, Ming, Johnson, Rolanda J., Escobedo, Jorge O., Beck, Patricia A., Kim, Kyu Kwang, St Luce, Nadia N., Davis, Claude J., Lewis, Patrick T., Fronczek, Frank R., Melancon, Bruce J., Mrse, Anthony A., Treleaven, W. Dale, Strongin, Robert M.
Publicerad 2002

Isatin replacements applied to the highly selective, muscarinic M(1) PAM ML137: Continued optimization of an MLPCN probe molecule

av Melancon, Bruce J., Poslusney, Michael S., Gentry, Patrick R., Tarr, James C., Sheffler, Douglas J., Mattmann, Margrith E., Bridges, Thomas M., Utley, Thomas J., Daniels, J. Scott, Niswender, Colleen M., Conn, P. Jeffrey, Lindsley, Craig W., Wood, Michael R.
Publicerad 2012

Development of novel M1 antagonist scaffolds through the continued optimization of the MLPCN probe ML012

av Melancon, Bruce J., Utley, Thomas J., Sevel, Christian, Mattmann, Margrith E., Cheung, Yiu-Yin, Bridges, Thomas M., Morrison, Ryan D., Sheffler, Douglas J., Niswender, Colleen M., Daniels, J. Scott, Conn, P. Jeffrey, Lindsley, Craig W., Wood, Michael R.
Publicerad 2012

Substituted indoles as selective protease activated receptor 4 (PAR-4) antagonists: Discovery and SAR of ML354

av Wen, Wandong, Young, Summer E., Duvernay, Matthew T., Schulte, Michael L., Nance, Kellie D., Melancon, Bruce J., Engers, Julie, Locuson, Charles W., Wood, Michael R., Daniels, J. Scott, Wu, Wenjun, Lindsley, Craig W., Hamm, Heidi E., Stauffer, Shaun R.
I publikationen Bioorg Med Chem Lett (2014)

Development of a Highly Selective, Orally Bioavailable and CNS Penetrant M(1) Agonist Derived from the MLPCN Probe ML071

av Lebois, Evan P., Digby, Gregory J., Sheffler, Douglas J., Melancon, Bruce J., Tarr, James C., Cho, Hyekyung P., Miller, Nicoel R., Morrison, Ryan, Bridges, Thomas M., Xiang, Zixiu, Daniels, J. Scott, Wood, Michael R., Conn, P. Jeffrey, Lindsley, Craig W.
Publicerad 2011

Development of a more highly selective M(1) antagonist from the continued optimization of the MLPCN Probe ML012

av Melancon, Bruce J., Lamers, Alexander P., Bridges, Thomas M., Sulikowski, Gary A., Utley, Thomas J., Sheffler, Douglas J., Noetzel, Meredith J., Morrison, Ryan D., Daniels, J. Scott, Niswender, Colleen M., Jones, Carrie K., Conn, P. Jeffrey, Lindsley, Craig W., Wood, Michael R.
Publicerad 2011

Discovery of Tricyclic Triazolo- and Imidazopyridine Lactams as M(1) Positive Allosteric Modulators

av Engers, Julie L., Bender, Aaron M., Kalbfleisch, Jacob J., Cho, Hyekyung P., Lingenfelter, Kaelyn S., Luscombe, Vincent B., Han, Changho, Melancon, Bruce J., Blobaum, Anna L., Dickerson, Jonathan W., Rook, Jerri M., Niswender, Colleen M., Emmitte, Kyle A., Conn, P. Jeffrey, Lindsley, Craig W.
I publikationen ACS Chem Neurosci (2018)

Inhibition of Histone Deacetylases 1, 2, and 3 Enhances Clearance of Cholesterol Accumulation in Niemann-Pick C1 Fibroblasts

av Cruz, Dana L., Pipalia, Nina, Mao, Shu, Gadi, Deepti, Liu, Gang, Grigalunas, Michael, O’Neill, Matthew, Quinn, Taylor R., Kipper, Andi, Ekebergh, Andreas, Dimmling, Alexander, Gartner, Carlos, Melancon, Bruce J., Wagner, Florence F., Holson, Edward, Helquist, Paul, Wiest, Olaf, Maxfield, Frederick R.
I publikationen ACS Pharmacol Transl Sci (2021)

Continued optimization of the MLPCN probe ML071 into highly potent agonists of the hM(1) muscarinic acetylcholine receptor

av Melancon, Bruce J., Gogliotti, Rocco D., Tarr, James C., Saleh, Sam A., Chauder, Brian A., Lebois, Evan P., Cho, Hyekyung P., Utley, Thomas J., Sheffler, Douglas J., Bridges, Thomas M., Morrison, Ryan D., Daniels, J. Scott, Niswender, Colleen M., Conn, P. Jeffrey, Lindsley, Craig W., Wood, Michael R.
Publicerad 2012

Discovery of a selective M(4) positive allosteric modulator based on the 3-amino-thieno[2,3-b]pyridine-2-carboxamide scaffold: development of ML253, a potent and brain penetrant co...

av Le, Uyen, Melancon, Bruce J., Bridges, Thomas M., Vinson, Paige N., Utley, Thomas J., Lamsal, Atin, Rodriguez, Alice L., Venable, Daryl, Sheffler, Douglas J., Jones, Carrie K., Blobaum, Anna L., Wood, Michael R., Daniels, J. Scott, Conn, P. Jeffrey, Niswender, Colleen M., Lindsley, Craig W., Hopkins, Corey R.
Publicerad 2012