Design, Synthesis, and Structure–Activity Relationship Studies of Fluorescent Inhibitors of Cycloxygenase-2 as Targeted Optical Imaging Agents

Autor Uddin, Md. Jashim, Crews, Brenda C., Ghebreselasie, Kebreab, Marnett, Lawrence J.
Vydáno 2013

Conjugates of Cisplatin and Cyclooxygenase Inhibitors as Potent Antitumor Agents Overcoming Cisplatin Resistance()

Autor Neumann, Wilma, Crews, Brenda C., Marnett, Lawrence J., Hey-Hawkins, Evamarie
Vydáno 2014

The glyceryl ester of prostaglandin E(2) mobilizes calcium and activates signal transduction in RAW264.7 cells

Autor Nirodi, Chaitanya S., Crews, Brenda C., Kozak, Kevin R., Morrow, Jason D., Marnett, Lawrence J.
Vydáno 2004

[(123)I]-Celecoxib Analogues as SPECT Tracers of Cyclooxygenase-2 in Inflammation

Autor Uddin, Md. Jashim, Crews, Brenda C., Ghebreselasie, Kebreab, Tantawy, Mohammed N., Marnett, Lawrence J.
Vydáno 2010

Total Synthesis of (+)-7-Bromotrypargine and Unnatural Analogues: Biological Evaluation Uncovers Activity at CNS Targets of Therapeutic Relevance

Autor Brogan, John T., Stoops, Sydney L., Crews, Brenda C., Marnett, Lawrence J., Lindsley, Craig W.
Vydáno 2011

Peroxynitrite, the coupling product of nitric oxide and superoxide, activates prostaglandin biosynthesis

Autor Landino, Lisa M., Crews, Brenda C., Timmons, Michael D., Morrow, Jason D., Marnett, Lawrence J.
Vydáno 1996

Trifluoromethyl Fluorocoxib A Detects Cyclooxygenase-2 Expression in Inflammatory Tissues and Human Tumor Xenografts

Autor Uddin, Md. Jashim, Crews, Brenda C., Huda, Imran, Ghebreselasie, Kebreab, Daniel, Cristina K., Marnett, Lawrence J.
Vydáno 2014

The 2′-Trifluoromethyl Analogue of Indomethacin Is a Potent and Selective COX-2 Inhibitor

Autor Blobaum, Anna L., Uddin, Md. Jashim, Felts, Andrew S., Crews, Brenda C., Rouzer, Carol A., Marnett, Lawrence J.
Vydáno 2013

Harmaline Analogs as Substrate-Selective Cyclooxygenase-2 Inhibitors

Autor Uddin, Md. Jashim, Xu, Shu, Crews, Brenda C., Aleem, Ansari M., Ghebreselasie, Kebreab, Banerjee, Surajit, Marnett, Lawrence J.
Vydáno v ACS Med Chem Lett (2020)

Structural determinants for calcium mobilization by prostaglandin E(2) and prostaglandin F(2α) glyceryl esters in RAW 264.7 cells and H1819 cells

Autor Richie-Jannetta, Robyn, Nirodi, Chaitanya S., Crews, Brenda C., Woodward, David F., Wang, Jenny W., Duff, Peter T., Marnett, Lawrence J.
Vydáno 2010

Targeted imaging of cancer by fluorocoxib C, a near-infrared cyclooxygenase-2 probe

Autor Uddin, Md. Jashim, Crews, Brenda C., Ghebreselasie, Kebreab, Daniel, Cristina K., Kingsley, Philip J., Xu, Shu, Marnett, Lawrence J.
Vydáno v J Biomed Opt (2015)

Biochemically based design of cyclooxygenase-2 (COX-2) inhibitors: Facile conversion of nonsteroidal antiinflammatory drugs to potent and highly selective COX-2 inhibitors

Autor Kalgutkar, Amit S., Crews, Brenda C., Rowlinson, Scott W., Marnett, Alan B., Kozak, Kevin R., Remmel, Rory P., Marnett, Lawrence J.
Vydáno 2000

Cyclooxygenase-1-Selective Inhibitors Based on the (E)-2′-Des-methyl-sulindac Sulfide Scaffold

Autor Liedtke, Andy J., Crews, Brenda C., Daniel, Cristina M., Blobaum, Anna L., Kingsley, Philip J., Ghebreselasie, Kebreab, Marnett, Lawrence J.
Vydáno 2012

Conjugation of Cisplatin Analogues and Cyclooxygenase Inhibitors to Overcome Cisplatin Resistance

Autor Neumann, Wilma, Crews, Brenda C., Sárosi, Menyhárt B., Daniel, Cristina M., Ghebreselasie, Kebreab, Scholz, Matthias S., Marnett, Lawrence J., Hey-Hawkins, Evamarie
Vydáno v ChemMedChem (2014)

Antitumor Activity of Cytotoxic Cyclooxygenase-2 Inhibitors

Autor Uddin, Md. Jashim, Crews, Brenda C., Xu, Shu, Ghebreselasie, Kebreab, Daniel, Cristina K., Kingsley, Philip J., Banerjee, Surajit, Marnett, Lawrence J.
Vydáno v ACS Chem Biol (2016)

Podophyllotoxin Analogues Active versus Trypanosoma brucei

Autor Uddin, Md. Jashim, Smithson, David C., Brown, Kristin M., Crews, Brenda C., Connelly, Michele, Zhu, Fangyi, Marnett, Lawrence J., Guy, R. Kiplin
Vydáno 2010

Design of Fluorine-Containing 3,4-Diarylfuran-2(5H)-ones as Selective COX-1 Inhibitors

Autor Uddin, Md. Jashim, Elleman, Anna V., Ghebreselasie, Kebreab, Daniel, Cristina K., Crews, Brenda C., Nance, Kellie D., Huda, Tamanna, Marnett, Lawrence J.
Vydáno v ACS Med Chem Lett (2014)

nido-Dicarbaborate Induces Potent and Selective Inhibition of Cyclooxygenase-2()

Autor Neumann, Wilma, Xu, Shu, Sárosi, Menyhárt B., Scholz, Matthias S., Crews, Brenda C., Ghebreselasie, Kebreab, Banerjee, Surajit, Marnett, Lawrence J., Hey-Hawkins, Evamarie
Vydáno v ChemMedChem (2015)

Fluorocoxib A enables targeted detection of cyclooxygenase-2 in laser-induced choroidal neovascularization

Autor Uddin, Md. Jashim, Moore, Chauca E., Crews, Brenda C., Daniel, Cristina K., Ghebreselasie, Kebreab, McIntyre, J. Oliver, Marnett, Lawrence J., Jayagopal, Ashwath
Vydáno v J Biomed Opt (2016)

Prostaglandin E(2) glyceryl ester is an endogenous agonist of the nucleotide receptor P2Y(6)

Autor Brüser, Antje, Zimmermann, Anne, Crews, Brenda C., Sliwoski, Gregory, Meiler, Jens, König, Gabriele M., Kostenis, Evi, Lede, Vera, Marnett, Lawrence J., Schöneberg, Torsten
Vydáno v Sci Rep (2017)