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Peroxynitrite, the coupling product of nitric oxide and superoxide, activates prostaglandin biosynthesis

Peroxynitrite activates the cyclooxygenase activities of constitutive and inducible prostaglandin endoperoxide synthases by serving as a substrate for the enzymes’ peroxidase activities. Activation of purified enzyme is induced by direct addition of peroxynitrite or by in situ generation of peroxyni...

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Detalhes bibliográficos
Main Authors: Landino, Lisa M., Crews, Brenda C., Timmons, Michael D., Morrow, Jason D., Marnett, Lawrence J.
Formato: Artigo
Idioma:Inglês
Publicado em: The National Academy of Sciences of the USA 1996
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC26357/
https://ncbi.nlm.nih.gov/pubmed/8986765
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