Peroxynitrite, the coupling product of nitric oxide and superoxide, activates prostaglandin biosynthesis
Peroxynitrite activates the cyclooxygenase activities of constitutive and inducible prostaglandin endoperoxide synthases by serving as a substrate for the enzymes’ peroxidase activities. Activation of purified enzyme is induced by direct addition of peroxynitrite or by in situ generation of peroxyni...
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| Publicat a: | Proc Natl Acad Sci U S A |
|---|---|
| Autors principals: | , , , , |
| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
National Academy of Sciences
1996
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26357/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8986765/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.26.15069 |
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