Peroxynitrite, the coupling product of nitric oxide and superoxide, activates prostaglandin biosynthesis

Peroxynitrite activates the cyclooxygenase activities of constitutive and inducible prostaglandin endoperoxide synthases by serving as a substrate for the enzymes’ peroxidase activities. Activation of purified enzyme is induced by direct addition of peroxynitrite or by in situ generation of peroxyni...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Landino, Lisa M., Crews, Brenda C., Timmons, Michael D., Morrow, Jason D., Marnett, Lawrence J.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1996
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26357/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8986765/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.26.15069
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