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Superoxide and peroxynitrite generation from inducible nitric oxide synthase in macrophages
Superoxide (O(2⨪)) and nitric oxide (NO) act to kill invading microbes in phagocytes. In macrophages NO is synthesized by inducible nitric oxide synthase (iNOS, NOS 2) from l-arginine (l-Arg) and oxygen; however, O(2⨪) was thought to be produced mainly by NADPH oxidase. Electron paramagnetic resonan...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences of the USA
1997
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC21266/ https://ncbi.nlm.nih.gov/pubmed/9192673 |
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