Superoxide and peroxynitrite generation from inducible nitric oxide synthase in macrophages
Superoxide (O(2⨪)) and nitric oxide (NO) act to kill invading microbes in phagocytes. In macrophages NO is synthesized by inducible nitric oxide synthase (iNOS, NOS 2) from l-arginine (l-Arg) and oxygen; however, O(2⨪) was thought to be produced mainly by NADPH oxidase. Electron paramagnetic resonan...
Gespeichert in:
| Veröffentlicht in: | Proc Natl Acad Sci U S A |
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| Hauptverfasser: | , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
National Academy of Sciences
1997
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| Schlagworte: | |
| Online-Zugang: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC21266/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9192673/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.94.13.6954 |
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