Nitric oxide synthase in cardiac sarcoplasmic reticulum

NO(⋅) is a free radical that modulates heart function and metabolism. We report that a neuronal-type NO synthase (NOS) is located on cardiac sarcoplasmic reticulum (SR) membrane vesicles and that endogenous NO(⋅) produced by SR-associated NOS inhibits SR Ca(2+) uptake. Ca(2+)-dependent biochemical c...

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Dades bibliogràfiques

Publicat a:	Proc Natl Acad Sci U S A
Autors principals:	Xu, Kai Y., Huso, David L., Dawson, Ted M., Bredt, David S., Becker, Lewis C.
Format:	Artigo
Idioma:	Inglês
Publicat:	National Academy of Sciences 1999
Matèries:	Biological Sciences
Accés en línia:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15192/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9892689/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.2.657
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