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Nitric oxide synthase in cardiac sarcoplasmic reticulum
NO(⋅) is a free radical that modulates heart function and metabolism. We report that a neuronal-type NO synthase (NOS) is located on cardiac sarcoplasmic reticulum (SR) membrane vesicles and that endogenous NO(⋅) produced by SR-associated NOS inhibits SR Ca(2+) uptake. Ca(2+)-dependent biochemical c...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
The National Academy of Sciences
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC15192/ https://ncbi.nlm.nih.gov/pubmed/9892689 |
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