Nitric oxide synthase in cardiac sarcoplasmic reticulum
NO(⋅) is a free radical that modulates heart function and metabolism. We report that a neuronal-type NO synthase (NOS) is located on cardiac sarcoplasmic reticulum (SR) membrane vesicles and that endogenous NO(⋅) produced by SR-associated NOS inhibits SR Ca(2+) uptake. Ca(2+)-dependent biochemical c...
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| Publicado no: | Proc Natl Acad Sci U S A |
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| Principais autores: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
1999
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC15192/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9892689/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.96.2.657 |
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