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Peroxynitrite, the coupling product of nitric oxide and superoxide, activates prostaglandin biosynthesis

Peroxynitrite activates the cyclooxygenase activities of constitutive and inducible prostaglandin endoperoxide synthases by serving as a substrate for the enzymes’ peroxidase activities. Activation of purified enzyme is induced by direct addition of peroxynitrite or by in situ generation of peroxyni...

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Bibliografische Detailangaben
Veröffentlicht in:Proc Natl Acad Sci U S A
Hauptverfasser: Landino, Lisa M., Crews, Brenda C., Timmons, Michael D., Morrow, Jason D., Marnett, Lawrence J.
Format: Artigo
Sprache:Inglês
Veröffentlicht: National Academy of Sciences 1996
Schlagworte:
Online-Zugang:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC26357/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/8986765/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.93.26.15069
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