Trifluoromethyl Fluorocoxib A Detects Cyclooxygenase-2 Expression in Inflammatory Tissues and Human Tumor Xenografts

[Image: see text] Fluorocoxib A is an effective COX-2-targeted optical imaging agent, used for in vivo detection of inflammatory tissues and premalignant and malignant tumors that express elevated levels of COX-2 (Uddin et al. Cancer Res. 2010, 70, 3618–3627). In an effort to discover novel optical...

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Main Authors: Uddin, Md. Jashim, Crews, Brenda C., Huda, Imran, Ghebreselasie, Kebreab, Daniel, Cristina K., Marnett, Lawrence J.
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2014
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC4027729/
https://ncbi.nlm.nih.gov/pubmed/24900856
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml400485g
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