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[(123)I]-Celecoxib Analogues as SPECT Tracers of Cyclooxygenase-2 in Inflammation
[Image: see text] We report the synthesis and evaluation of a series of iodinated celecoxib analogues as cyclooxygenase-2 (COX-2)-targeted single photon emission computerized tomography (SPECT) imaging agents for the detection of inflammation. The structure−activity relationship identified 5-(4-iodo...
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| Main Authors: | , , , , |
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| Format: | Artigo |
| Jezik: | Inglês |
| Izdano: |
American Chemical Society
2010
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| Online dostop: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3037034/ https://ncbi.nlm.nih.gov/pubmed/21318094 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml100232q |
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