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Fluorinated Cyclooxygenase-2 Inhibitors as Agents in PET Imaging of Inflammation and Cancer

Cyclooxygenase-2 (COX-2) is a major contributor to the inflammatory response and cancer progression so it is an important target for prevention and therapy. COX-2 is absent or expressed at low levels in most epithelial cells but is found at high levels in inflammatory lesions, and many premalignant...

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Hlavní autoři: Uddin, Md. Jashim, Crews, Brenda C., Ghebreselasie, Kebreab, Huda, Imran, Kingsley, Philip J., Ansari, M. Sib, Tantawy, Mohammed N., Reese, J. Jeffery, Marnett, Lawrence J.
Médium: Artigo
Jazyk:Inglês
Vydáno: 2011
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3214660/
https://ncbi.nlm.nih.gov/pubmed/21900596
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1158/1940-6207.CAPR-11-0120
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