HIV-1 Resistance to the Capsid-Targeting Inhibitor PF74 Results in Altered Dependence on Host Factors Required for Virus Nuclear Entry

Por Zhou, Jing, Price, Amanda J., Halambage, Upul D., James, Leo C., Aiken, Christopher
Publicado no J Virol (2015)

Microplate-Based Assay for Identifying Small Molecules That Bind a Specific Intersubunit Interface within the Assembled HIV-1 Capsid

Por Halambage, Upul D., Wong, Jason P., Melancon, Bruce J., Lindsley, Craig W., Aiken, Christopher
Publicado no Antimicrob Agents Chemother (2015)

Inhibition of HIV-1 Maturation via Small-Molecule Targeting of the Amino-Terminal Domain in the Viral Capsid Protein

Por Wang, Weifeng, Zhou, Jing, Halambage, Upul D., Jurado, Kellie A., Jamin, Augusta V., Wang, Yujie, Engelman, Alan N., Aiken, Christopher
Publicado no J Virol (2017)

Compensatory Substitutions in the HIV-1 Capsid Reduce the Fitness Cost Associated with Resistance to a Capsid-Targeting Small-Molecule Inhibitor

Por Shi, Jiong, Zhou, Jing, Halambage, Upul D., Shah, Vaibhav B., Burse, Mallori J., Wu, Hua, Blair, Wade S., Butler, Scott L., Aiken, Christopher
Publicado no J Virol (2014)

Host Cofactors and Pharmacologic Ligands Share an Essential Interface in HIV-1 Capsid That Is Lost upon Disassembly

Por Price, Amanda J., Jacques, David A., McEwan, William A., Fletcher, Adam J., Essig, Sebastian, Chin, Jason W., Halambage, Upul D., Aiken, Christopher, James, Leo C.
Publicado em 2014

Roles of Capsid-Interacting Host Factors in Multimodal Inhibition of HIV-1 by PF74

Por Saito, Akatsuki, Ferhadian, Damien, Sowd, Gregory A., Serrao, Erik, Shi, Jiong, Halambage, Upul D., Teng, Samantha, Soto, Juan, Siddiqui, Mohammad Adnan, Engelman, Alan N., Aiken, Christopher, Yamashita, Masahiro
Publicado no J Virol (2016)