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Microplate-Based Assay for Identifying Small Molecules That Bind a Specific Intersubunit Interface within the Assembled HIV-1 Capsid

Despite the availability of >30 effective drugs for managing HIV-1 infection, no current therapy is curative, and long-term management is challenging owing to the emergence and spread of drug-resistant mutants. Identification of drugs against novel HIV-1 targets would expand the current treatment...

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Detalhes bibliográficos
Publicado no:Antimicrob Agents Chemother
Main Authors: Halambage, Upul D., Wong, Jason P., Melancon, Bruce J., Lindsley, Craig W., Aiken, Christopher
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4538492/
https://ncbi.nlm.nih.gov/pubmed/26077250
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.00646-15
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