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The NTD-CTD intersubunit interface plays a critical role in assembly and stabilization of the HIV-1 capsid
BACKGROUND: Lentiviruses exhibit a cone-shaped capsid composed of subunits of the viral CA protein. The intrinsic stability of the capsid is critical for HIV-1 infection, since both stabilizing and destabilizing mutations compromise viral infectivity. Structural studies have identified three intersu...
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| Main Authors: | , |
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| Format: | Artigo |
| Language: | Inglês |
| Published: |
BioMed Central
2013
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3623829/ https://ncbi.nlm.nih.gov/pubmed/23497318 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1742-4690-10-29 |
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