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TRIM5α Disrupts the Structure of Assembled HIV-1 Capsid Complexes In Vitro
The host restriction factor TRIM5α provides intrinsic defense against retroviral infections in mammalian cells. TRIM5α blocks infection by targeting the viral capsid after entry but prior to completion of reverse transcription, but whether this interaction directly alters the structure of the viral...
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| Huvudupphovsmän: | , |
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| Materialtyp: | Artigo |
| Språk: | Inglês |
| Publicerad: |
American Society for Microbiology (ASM)
2010
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| Länkar: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2903270/ https://ncbi.nlm.nih.gov/pubmed/20410272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/JVI.00210-10 |
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