Structural insight into HIV-1 capsid recognition by rhesus TRIM5α

Tripartite motif protein isoform 5 alpha (TRIM5α) is a potent antiviral protein that restricts infection by HIV-1 and other retroviruses. TRIM5α recognizes the lattice of the retrovirus capsid through its B30.2 (PRY/SPRY) domain in a species-specific manner. Upon binding, TRIM5α induces premature di...

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Bibliografiske detaljer
Main Authors: Yang, Haitao, Ji, Xiaoyun, Zhao, Gongpu, Ning, Jiying, Zhao, Qi, Aiken, Christopher, Gronenborn, Angela M., Zhang, Peijun, Xiong, Yong
Format: Artigo
Sprog:Inglês
Udgivet: National Academy of Sciences 2012
Fag:
Biological Sciences
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3494900/
https://ncbi.nlm.nih.gov/pubmed/23091002
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1210903109
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