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Protease Cleavage Leads to Formation of Mature Trimer Interface in HIV-1 Capsid

During retrovirus particle maturation, the assembled Gag polyprotein is cleaved by the viral protease into matrix (MA), capsid (CA), and nucleocapsid (NC) proteins. To form the mature viral capsid, CA rearranges, resulting in a lattice composed of hexameric and pentameric CA units. Recent structural...

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Main Authors: Meng, Xin, Zhao, Gongpu, Yufenyuy, Ernest, Ke, Danxia, Ning, Jiying, DeLucia, Maria, Ahn, Jinwoo, Gronenborn, Angela M., Aiken, Christopher, Zhang, Peijun
格式: Artigo
語言:Inglês
出版: Public Library of Science 2012
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在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426514/
https://ncbi.nlm.nih.gov/pubmed/22927821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002886
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