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Protease Cleavage Leads to Formation of Mature Trimer Interface in HIV-1 Capsid
During retrovirus particle maturation, the assembled Gag polyprotein is cleaved by the viral protease into matrix (MA), capsid (CA), and nucleocapsid (NC) proteins. To form the mature viral capsid, CA rearranges, resulting in a lattice composed of hexameric and pentameric CA units. Recent structural...
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| Main Authors: | , , , , , , , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
Public Library of Science
2012
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3426514/ https://ncbi.nlm.nih.gov/pubmed/22927821 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002886 |
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