Protease Cleavage Leads to Formation of Mature Trimer Interface in HIV-1 Capsid

During retrovirus particle maturation, the assembled Gag polyprotein is cleaved by the viral protease into matrix (MA), capsid (CA), and nucleocapsid (NC) proteins. To form the mature viral capsid, CA rearranges, resulting in a lattice composed of hexameric and pentameric CA units. Recent structural...

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Detalhes bibliográficos
Main Authors: Meng, Xin, Zhao, Gongpu, Yufenyuy, Ernest, Ke, Danxia, Ning, Jiying, DeLucia, Maria, Ahn, Jinwoo, Gronenborn, Angela M., Aiken, Christopher, Zhang, Peijun
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3426514/
https://ncbi.nlm.nih.gov/pubmed/22927821
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1002886
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