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In vitro protease cleavage and computer simulations reveal the HIV-1 capsid maturation pathway

HIV-1 virions assemble as immature particles containing Gag polyproteins that are processed by the viral protease into individual components, resulting in the formation of mature infectious particles. There are two competing models for the process of forming the mature HIV-1 core: the disassembly an...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Nat Commun
Prif Awduron: Ning, Jiying, Erdemci-Tandogan, Gonca, Yufenyuy, Ernest L., Wagner, Jef, Himes, Benjamin A., Zhao, Gongpu, Aiken, Christopher, Zandi, Roya, Zhang, Peijun
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: Nature Publishing Group 2016
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159922/
https://ncbi.nlm.nih.gov/pubmed/27958264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13689
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