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In vitro protease cleavage and computer simulations reveal the HIV-1 capsid maturation pathway

HIV-1 virions assemble as immature particles containing Gag polyproteins that are processed by the viral protease into individual components, resulting in the formation of mature infectious particles. There are two competing models for the process of forming the mature HIV-1 core: the disassembly an...

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Détails bibliographiques
Publié dans:Nat Commun
Auteurs principaux: Ning, Jiying, Erdemci-Tandogan, Gonca, Yufenyuy, Ernest L., Wagner, Jef, Himes, Benjamin A., Zhao, Gongpu, Aiken, Christopher, Zandi, Roya, Zhang, Peijun
Format: Artigo
Langue:Inglês
Publié: Nature Publishing Group 2016
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5159922/
https://ncbi.nlm.nih.gov/pubmed/27958264
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms13689
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