Structural Convergence between CryoEM and NMR Reveals Novel Intersubunit Interactions Critical for HIV-1 Capsid Function

Mature HIV-1 particles contain conical-shaped capsids that enclose the viral RNA genome and perform essential functions in the virus life cycle. Previous structural analysis of two and three-dimensional arrays provided a molecular model of the capsid protein (CA) hexamer and revealed three interface...

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Autores principales: Byeon, In-Ja L., Meng, Xin, Jung, Jinwon, Zhao, Gongpu, Yang, Ruifeng, Ahn, Jinwoo, Shi, Jiong, Concel, Jason, Aiken, Christopher, Zhang, Peijun, Gronenborn, Angela M.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2009
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC2782912/
https://ncbi.nlm.nih.gov/pubmed/19914170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cell.2009.10.010
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