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CryoEM Structure Refinement by Integrating NMR Chemical Shifts with Molecular Dynamics Simulations

Single particle cryoEM has emerged as a powerful method for structure determination of proteins and complexes, complementing X-ray crystallography and NMR spectroscopy. Yet, for many systems, the resolution of cryoEM density map has been limited to 4–6 Å, which only allows for resolving bulky amino...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Argitaratua izan da:J Phys Chem B
Egile Nagusiak: Perilla, Juan R., Zhao, Gongpu, Lu, Manman, Ning, Jiying, Hou, Guangjin, Byeon, In-Ja L., Gronenborn, Angela M., Polenova, Tatyana, Zhang, Peijun
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2017
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC5459578/
https://ncbi.nlm.nih.gov/pubmed/28181439
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acs.jpcb.6b13105
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