Small Molecules that Modulate Quorum Sensing and Control Virulence in Pseudomonas aeruginosa

द्वारा Mattmann, Margrith E., Blackwell, Helen E.
प्रकाशित 2010

Evaluation of a focused library of N-aryl L-homoserine lactones reveals a new set of potent quorum sensing modulators

द्वारा Geske, Grant D., Mattmann, Margrith E., Blackwell, Helen E.
प्रकाशित 2008

Recent progress in the discovery of small molecules for the treatment of amyotrophic lateral sclerosis (ALS)

द्वारा Limpert, Allison S, Mattmann, Margrith E, Cosford, Nicholas D P
प्रकाशित 2013

Inhibition of Akt with small molecules and biologics: historical perspective and current status of the patent landscape

द्वारा Mattmann, Margrith E, Stoops, Sydney L, Lindsley, Craig W
में प्रकाशित Expert Opin Ther Pat (2011)

Potent and Selective Synthetic Modulators of a Quorum Sensing Repressor in Pseudomonas aeruginosa Identified from Second-Generation Libraries of N-Acylated l-Homoserine Lactones

द्वारा Mattmann, Margrith E., Shipway, Patrick M., Heth, Nicole J., Blackwell, Helen E.
प्रकाशित 2011

Potent and Selective Modulation of the RhlR Quorum Sensing Receptor using Non-Native Ligands – An Emerging Target for Virulence Control in Pseudomonas aeruginosa

द्वारा Eibergen, Nora R., Moore, Joseph D., Mattmann, Margrith E., Blackwell, Helen E.
में प्रकाशित Chembiochem (2015)

Modulation of Bacterial Quorum Sensing with Synthetic Ligands: Systematic Evaluation of N-Acylated Homoserine Lactones in Multiple Species and New Insights into Their Mechanisms of...

द्वारा Geske, Grant D., O’Neill, Jennifer C., Miller, David M., Mattmann, Margrith E., Blackwell, Helen E.
प्रकाशित 2007

Comparative Analyses of N-Acylated Homoserine Lactones Reveal Unique Structural Features that Dictate Their Ability to Activate or Inhibit Quorum Sensing

द्वारा Geske, Grant D., O’Neill, Jennifer C., Miller, David M., Wezeman, Rachel J., Mattmann, Margrith E., Lin, Qi, Blackwell, Helen E.
प्रकाशित 2008

An integrated chemical biology approach reveals the mechanism of action of HIV replication inhibitors

द्वारा Pagano, Nicholas, Teriete, Peter, Mattmann, Margrith E., Yang, Li, Snyder, Beth A., Cai, Zhaohui, Heil, Marintha L., Cosford, Nicholas D.P.
में प्रकाशित Bioorg Med Chem (2017)

Isovaleryl-homoserine lactone, an unusual branched-chain quorum-sensing signal from the soybean symbiont Bradyrhizobium japonicum

द्वारा Lindemann, Andrea, Pessi, Gabriella, Schaefer, Amy L., Mattmann, Margrith E., Christensen, Quin H., Kessler, Aline, Hennecke, Hauke, Blackwell, Helen E., Greenberg, E. Peter, Harwood, Caroline S.
प्रकाशित 2011

Control of Quorum Sensing by a Burkholderia pseudomallei Multidrug Efflux Pump

द्वारा Chan, Ying Ying, Bian, Hao Sheng, Tan, Theresa May Chin, Mattmann, Margrith E., Geske, Grant D., Igarashi, Jun, Hatano, Tomomi, Suga, Hiroaki, Blackwell, Helen E., Chua, Kim Lee
प्रकाशित 2007

Dynamic subunit stoichiometry confers a progressive continuum of pharmacological sensitivity by KCNQ potassium channels

द्वारा Yu, Haibo, Lin, Zhihong, Mattmann, Margrith E., Zou, Beiyan, Terrenoire, Cecile, Zhang, Hongkang, Wu, Meng, McManus, Owen B., Kass, Robert S., Lindsley, Craig W., Hopkins, Corey R., Li, Min
प्रकाशित 2013

Identification of (R)-N-(4-(4-methoxyphenyl)thiazol-2-yl)-1-tosylpiperidine-2-carboxamide, ML277, as a novel, potent and selective K(v)7.1 (KCNQ1) potassium channel activator

द्वारा Mattmann, Margrith E., Yu, Haibo, Lin, Zhihong, Xu, Kaiping, Huang, Xiaofang, Long, Shunyou, Wu, Meng, McManus, Owen B., Engers, Darren W., Le, Uyen M., Li, Min, Lindsley, Craig W., Hopkins, Corey R.
प्रकाशित 2012

Isatin replacements applied to the highly selective, muscarinic M(1) PAM ML137: Continued optimization of an MLPCN probe molecule

द्वारा Melancon, Bruce J., Poslusney, Michael S., Gentry, Patrick R., Tarr, James C., Sheffler, Douglas J., Mattmann, Margrith E., Bridges, Thomas M., Utley, Thomas J., Daniels, J. Scott, Niswender, Colleen M., Conn, P. Jeffrey, Lindsley, Craig W., Wood, Michael R.
प्रकाशित 2012

Development of novel M1 antagonist scaffolds through the continued optimization of the MLPCN probe ML012

द्वारा Melancon, Bruce J., Utley, Thomas J., Sevel, Christian, Mattmann, Margrith E., Cheung, Yiu-Yin, Bridges, Thomas M., Morrison, Ryan D., Sheffler, Douglas J., Niswender, Colleen M., Daniels, J. Scott, Conn, P. Jeffrey, Lindsley, Craig W., Wood, Michael R.
प्रकाशित 2012

Heterotropic Activation of the Midazolam Hydroxylase Activity of CYP3A by a Positive Allosteric Modulator of mGlu(5): In Vitro to In Vivo Translation and Potential Impact on Clinic...

द्वारा Blobaum, Anna L., Bridges, Thomas M., Byers, Frank W., Turlington, Mark L., Mattmann, Margrith E., Morrison, Ryan D., Mackie, Claire, Lavreysen, Hilde, Bartolomé, José M., MacDonald, Gregor J., Steckler, Thomas, Jones, Carrie K., Niswender, Colleen M., Conn, P. Jeffrey, Lindsley, Craig W., Stauffer, Shaun R., Daniels, J. Scott
प्रकाशित 2013

Identification of Positive Allosteric Modulators VU0155094 (ML397) and VU0422288 (ML396) Reveals New Insights into the Biology of Metabotropic Glutamate Receptor 7

द्वारा Jalan-Sakrikar, Nidhi, Field, Julie R., Klar, Rebecca, Mattmann, Margrith E., Gregory, Karen J., Zamorano, Rocio, Engers, Darren W., Bollinger, Sean R., Weaver, C. David, Days, Emily L., Lewis, L. Michelle, Utley, Thomas J., Hurtado, Miguel, Rigault, Delphine, Acher, Francine, Walker, Adam G., Melancon, Bruce J., Wood, Michael R., Lindsley, Craig W., Conn, P. Jeffrey, Xiang, Zixiu, Hopkins, Corey R., Niswender, Colleen M.
में प्रकाशित ACS Chem Neurosci (2014)