Effect of tyrphostin AG879 on K(v)4.2 and K(v)4.3 potassium channels

Por Yu, Haibo, Zou, Beiyan, Wang, Xiaoliang, Li, Min
Publicado no Br J Pharmacol (2015)

Reporting Sodium Channel Activity Using Calcium Flux: Pharmacological Promiscuity of Cardiac Nav1.5

Por Zhang, Hongkang, Zou, Beiyan, Du, Fang, Xu, Kaiping, Li, Min
Publicado no Mol Pharmacol (2015)

Global Analysis Reveals Families of Chemical Motifs Enriched for hERG Inhibitors

Por Du, Fang, Babcock, Joseph J., Yu, Haibo, Zou, Beiyan, Li, Min
Publicado no PLoS One (2015)

hERGCentral: A Large Database to Store, Retrieve, and Analyze Compound-Human Ether-à-go-go Related Gene Channel Interactions to Facilitate Cardiotoxicity Assessment in Drug Develop...

Por Du, Fang, Yu, Haibo, Zou, Beiyan, Babcock, Joseph, Long, Shunyou, Li, Min
Publicado em 2011

Identification of novel small molecule modulators of K(2P)18.1 two-pore potassium channel

Por Bruner, J. Kyle, Zou, Beiyan, Zhang, Hongkang, Zhang, Yixin, Schmidt, Katharina, Li, Min
Publicado no Eur J Pharmacol (2014)

Profiling Diverse Compounds by Flux- and Electrophysiology-Based Primary Screens for Inhibition of Human Ether-à-go-go Related Gene Potassium Channels

Por Zou, Beiyan, Yu, Haibo, Babcock, Joseph J., Chanda, Pritam, Bader, Joel S., McManus, Owen B., Li, Min
Publicado em 2010

Discovery of a Series of 2-phenyl-N-(2-(pyrrolidin-1-yl)phenyl)acetamides as Novel Molecular Switches that Modulate Modes of K(v)7.2 (KCNQ2) Channel Pharmacology: Identification of...

Por Cheung, Yiu-Yin, Yu, Haibo, Xu, Kaiping, Zou, Beiyan, Wu, Meng, McManus, Owen B., Li, Min, Lindsley, Craig W., Hopkins, Corey R.
Publicado em 2012

Discovery, Synthesis, and Structure–Activity Relationship of a Series of N-Aryl-bicyclo[2.2.1]heptane-2-carboxamides: Characterization of ML213 as a Novel KCNQ2 and KCNQ4 Potassium...

Por Yu, Haibo, Wu, Meng, Townsend, Steven D., Zou, Beiyan, Long, Shunyou, Daniels, J. Scott, McManus, Owen B., Li, Min, Lindsley, Craig W., Hopkins, Corey R.
Publicado em 2011

Potent and selective inhibitors of the TASK-1 potassium channel through chemical optimization of a bis-amide scaffold

Por Flaherty, Daniel P., Simpson, Denise S., Miller, Melissa, Maki, Brooks E., Zou, Beiyan, Shi, Jie, Wu, Meng, McManus, Owen B., Aubé, Jeffrey, Li, Min, Golden, Jennifer E.
Publicado em 2014

Dynamic subunit stoichiometry confers a progressive continuum of pharmacological sensitivity by KCNQ potassium channels

Por Yu, Haibo, Lin, Zhihong, Mattmann, Margrith E., Zou, Beiyan, Terrenoire, Cecile, Zhang, Hongkang, Wu, Meng, McManus, Owen B., Kass, Robert S., Lindsley, Craig W., Hopkins, Corey R., Li, Min
Publicado em 2013

Modulation of hERG potassium channel gating normalizes action potential duration prolonged by dysfunctional KCNQ1 potassium channel

Por Zhang, Hongkang, Zou, Beiyan, Yu, Haibo, Moretti, Alessandra, Wang, Xiaoying, Yan, Wei, Babcock, Joseph J., Bellin, Milena, McManus, Owen B., Tomaselli, Gordon, Nan, Fajun, Laugwitz, Karl-Ludwig, Li, Min
Publicado em 2012

Identification and Characterization of a Compound That Protects Cardiac Tissue from Human Ether-à-go-go-related Gene (hERG)-related Drug-induced Arrhythmias

Por Potet, Franck, Lorinc, Amanda N., Chaigne, Sebastien, Hopkins, Corey R., Venkataraman, Raghav, Stepanovic, Svetlana Z., Lewis, L. Michelle, Days, Emily, Sidorov, Veniamin Y., Engers, Darren W., Zou, Beiyan, Afshartous, David, George, Alfred L., Campbell, Courtney M., Balser, Jeffrey R., Li, Min, Baudenbacher, Franz J., Lindsley, Craig W., Weaver, C. David, Kupershmidt, Sabina
Publicado em 2012

Advancing Biological Understanding and Therapeutics Discovery with Small Molecule Probes

Por Schreiber, Stuart L., Kotz, Joanne D., Li, Min, Aubé, Jeffrey, Austin, Christopher P., Reed, John C., Rosen, Hugh, White, E. Lucile, Sklar, Larry A., Lindsley, Craig W., Alexander, Benjamin R., Bittker, Joshua A., Clemons, Paul A., de Souza, Andrea, Foley, Michael A., Palmer, Michelle, Shamji, Alykhan F., Wawer, Mathias J., McManus, Owen, Wu, Meng, Zou, Beiyan, Yu, Haibo, Golden, Jennifer E., Schoenen, Frank J., Simeonov, Anton, Jadhav, Ajit, Jackson, Michael R., Pinkerton, Anthony B., Chung, Thomas D.Y., Griffin, Patrick R., Cravatt, Benjamin F., Hodder, Peter S., Roush, William R., Roberts, Edward, Chung, Dong-Hoon, Jonsson, Colleen B., Noah, James W., Severson, William E., Ananthan, Subramaniam, Edwards, Bruce, Oprea, Tudor I., Conn, P. Jeffrey, Hopkins, Corey R., Wood, Michael R., Stauffer, Shaun R., Emmitte, Kyle A.
Publicado no Cell (2015)