Antinociceptive Effects of Herkinorin, a MOP Receptor Agonist Derived from Salvinorin A in the Formalin Test in Rats: New Concepts in Mu Opioid Receptor Pharmacology()

Por Lamb, Kenneth, Tidgewell, Kevin, Simpson, Denise S., Bohn, Laura M., Prisinzano, Thomas E.
Publicado em 2011

The effects of herkinorin, the first μ-selective ligand from a salvinorin A-derived scaffold, in a neuroendocrine biomarker assay in non-human primates

Por Butelman, Eduardo R., Rus, Szymon, Simpson, Denise S., Wolf, Angela, Prisinzano, Thomas E., Kreek, Mary Jeanne
Publicado em 2008

Current Usage Patterns and Attitudes Toward Handheld Computers in Clinical Care

Por Churchill, Brian E., Jimison, Holly, Lyman, Jason A., Mailhot, Mark F., Quick, Edwin A., Simpson, Denise A.
Publicado em 2000

Synthetic Studies of Neoclerodane Diterpenes from Salvia divinorum: Role of the Furan in Affinity for Opioid Receptors

Por Simpson, Denise S., Lovell, Kimberly M., Lozama, Anthony, Han, Nina, Day, Victor W., Dersch, Christina M., Rothman, Richard B., Prisinzano, Thomas E.
Publicado em 2009

DIFFERENTIAL EFFECTS OF OPIOID AGONISTS ON G PROTEIN EXPRESSION IN CHO CELLS EXPRESSING CLONED HUMAN OPIOID RECEPTORS

Por Xu, Heng, Wang, Xiaoying, Partilla, John S., Bishop-Mathis, Kristen, Benaderet, Tova S., Dersch, Christina M., Simpson, Denise S., Prisinzano, Thomas E., Rothman, Richard B.
Publicado em 2008

Potential Drug Abuse Therapeutics Derived from the Hallucinogenic Natural Product Salvinorin A

Por Prevatt-Smith, Katherine M., Lovell, Kimberly M., Simpson, Denise S., Day, Victor W., Douglas, Justin T., Bosch, Peter, Dersch, Christina M., Rothman, Richard B., Kivell, Bronwyn, Prisinzano, Thomas E.
Publicado em 2011

Potent and selective inhibitors of the TASK-1 potassium channel through chemical optimization of a bis-amide scaffold

Por Flaherty, Daniel P., Simpson, Denise S., Miller, Melissa, Maki, Brooks E., Zou, Beiyan, Shi, Jie, Wu, Meng, McManus, Owen B., Aubé, Jeffrey, Li, Min, Golden, Jennifer E.
Publicado em 2014

Ebselen Inhibits Hepatitis C Virus NS3 Helicase Binding to Nucleic Acid and Prevents Viral Replication

Por Mukherjee, Sourav, Weiner, Warren S., Schroeder, Chad E., Simpson, Denise S., Hanson, Alicia M., Sweeney, Noreena L., Marvin, Rachel K., Ndjomou, Jean, Kolli, Rajesh, Isailovic, Dragan, Schoenen, Frank J., Frick, David N.
Publicado em 2014

Optimization of Potent and Selective Quinazolinediones: Inhibitors of Respiratory Syncytial Virus That Block RNA-Dependent RNA-Polymerase Complex Activity

Por Matharu, Daljit S., Flaherty, Daniel P., Simpson, Denise S., Schroeder, Chad E., Chung, Donghoon, Yan, Dan, Noah, James W., Jonsson, Colleen B., White, E. Lucile, Aubé, Jeffrey, Plemper, Richard K., Severson, William E., Golden, Jennifer E.
Publicado no J Med Chem (2014)

Identification of a Novel “Almost Neutral” Mu Opioid Receptor Antagonist in CHO Cells Expressing the Cloned Human Mu Opioid Receptor

Por Sally, Elliott J., Xu, Heng, Dersch, Christina M., Hsin, Ling-Wei, Chang, Li-Te, Prisinzano, Thomas E., Simpson, Denise S., Giuvelis, Denise, Rice, Kenner C., Jacobson, Arthur E., Cheng, Kejun, Bilsky, Edward J., Rothman, Richard B.
Publicado em 2010

A Competitive Nucleotide Binding Inhibitor: In vitro Characterization of Rab7 GTPase Inhibition

Por Agola, Jacob O., Hong, Lin, Surviladze, Zurab, Ursu, Oleg, Waller, Anna, Strouse, J. Jacob, Simpson, Denise S., Schroeder, Chad E., Oprea, Tudor I., Golden, Jennifer E., Aubé, Jeffrey, Buranda, Tione, Sklar, Larry A., Wandinger-Ness, Angela
Publicado em 2012

A Pan-GTPase Inhibitor as a Molecular Probe

Por Hong, Lin, Guo, Yuna, BasuRay, Soumik, Agola, Jacob O., Romero, Elsa, Simpson, Denise S., Schroeder, Chad E., Simons, Peter, Waller, Anna, Garcia, Matthew, Carter, Mark, Ursu, Oleg, Gouveia, Kristine, Golden, Jennifer E., Aubé, Jeffrey, Wandinger-Ness, Angela, Sklar, Larry A.
Publicado no PLoS One (2015)

Characterization of a Cdc42 Protein Inhibitor and Its Use as a Molecular Probe

Por Hong, Lin, Kenney, S. Ray, Phillips, Genevieve K., Simpson, Denise, Schroeder, Chad E., Nöth, Julica, Romero, Elsa, Swanson, Scarlett, Waller, Anna, Strouse, J. Jacob, Carter, Mark, Chigaev, Alexandre, Ursu, Oleg, Oprea, Tudor, Hjelle, Brian, Golden, Jennifer E., Aubé, Jeffrey, Hudson, Laurie G., Buranda, Tione, Sklar, Larry A., Wandinger-Ness, Angela
Publicado em 2013

Characterization of a Cdc42 protein inhibitor and its use as a molecular probe.

Por Hong, Lin, Kenney, S. Ray, Phillips, Genevieve K., Simpson, Denise, Schroeder, Chad E., Nöth, Julica, Romero, Elsa, Swanson, Scarlett, Waller, Anna, Strouse, J. Jacob, Carter, Mark, Chigaev, Alexandre, Ursu, Oleg, Oprea, Tudor, Hjelle, Brian, Golden, Jennifer E., Aubé, Jeffrey, Hudson, Laurie G., Buranda, Tione, Sklar, Larry A., Wandinger-Ness, Angela
Publicado em 2014

A Selective ATP-binding Cassette Sub-family G Member 2 Efflux Inhibitor Revealed Via High-Throughput Flow Cytometry

Por Strouse, J. Jacob, Ivnitski-Steele, Irena, Khawaja, Hadya M., Perez, Dominique, Ricci, Jerec, Yao, Tuanli, Weiner, Warren S., Schroeder, Chad E., Simpson, Denise S., Maki, Brooks E., Li, Kelin, Golden, Jennifer E., Foutz, Terry D., Waller, Anna, Evangelisti, Annette M., Young, Susan M., Chavez, Stephanie E., Garcia, Matthew J., Ursu, Oleg, Bologa, Cristian G., Carter, Mark B., Salas, Virginia M., Gouveia, Kristine, Tegos, George P., Oprea, Tudor I., Edwards, Bruce S., Aubé, Jeffrey, Larson, Richard S., Sklar, Larry A.
Publicado em 2012