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The effects of herkinorin, the first μ-selective ligand from a salvinorin A-derived scaffold, in a neuroendocrine biomarker assay in non-human primates
Herkinorin is the first μ-opioid receptor (MOP-r) selective ligand from the salvinorin A diterpenoid scaffold. Herkinorin has relative μ>κ>δ binding selectivity, and can act as an agonist at both μ- and κ-receptors, in vitro. These studies were the first in vivo evaluation of herkinorin's...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2008
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2614932/ https://ncbi.nlm.nih.gov/pubmed/18593955 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1124/jpet.108.140079 |
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