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Salvinorin A, a kappa-opioid receptor agonist hallucinogen: pharmacology and potential template for novel pharmacotherapeutic agents in neuropsychiatric disorders

Salvinorin A is a potent hallucinogen, isolated from the ethnomedical plant Salvia divinorum. Salvinorin A is a selective high efficacy kappa-opioid receptor (KOPr) agonist, and thus implicates the KOPr system and its endogenous agonist ligands (the dynorphins) in higher functions, including cogniti...

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Detalhes bibliográficos
Publicado no:Front Pharmacol
Principais autores: Butelman, Eduardo R., Kreek, Mary Jeanne
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4561799/
https://ncbi.nlm.nih.gov/pubmed/26441647
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2015.00190
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