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Kappa opioid receptor/dynorphin system: Genetic and pharmacotherapeutic implications for addiction
Addictions to cocaine or heroin/prescription opioids [short-acting mu-opioid receptor (MOPr) agonists] involve relapsing cycles, with experimentation/escalating use, withdrawal/abstinence, and relapse/re-escalation. Kappa-opioid receptors (KOPr; encoded by OPRK1), and their endogenous agonists, the...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3685470/ https://ncbi.nlm.nih.gov/pubmed/22709632 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2012.05.005 |
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