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Kappa opioid receptor/dynorphin system: Genetic and pharmacotherapeutic implications for addiction

Addictions to cocaine or heroin/prescription opioids [short-acting mu-opioid receptor (MOPr) agonists] involve relapsing cycles, with experimentation/escalating use, withdrawal/abstinence, and relapse/re-escalation. Kappa-opioid receptors (KOPr; encoded by OPRK1), and their endogenous agonists, the...

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Bibliografski detalji
Glavni autori: Butelman, Eduardo R., Yuferov, Vadim, Kreek, Mary Jeanne
Format: Artigo
Jezik:Inglês
Izdano: 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3685470/
https://ncbi.nlm.nih.gov/pubmed/22709632
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.tins.2012.05.005
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