iPHACE: integrative navigation in pharmacological space

gan Garcia-Serna, Ricard, Ursu, Oleg, Oprea, Tudor I., Mestres, Jordi
Cyhoeddwyd 2010

Erratum to: Impact of similarity threshold on the topology of molecular similarity networks and clustering outcomes

gan Zahoránszky-Kőhalmi, Gergely, Bologa, Cristian G., Ursu, Oleg, Oprea, Tudor I.
Cyhoeddwyd yn J Cheminform (2016)

BDDCS, the Rule of 5 and Drugability

gan Benet, Leslie Z., Hosey, Chelsea M., Ursu, Oleg, Oprea, Tudor I.
Cyhoeddwyd yn Adv Drug Deliv Rev (2016)

CHEMICAL AND BIOLOGICAL DESCRIPTOR INTEGRATION IMPROVES COMPUTATIONAL MODELING OF IN VIVO RAT TOXICITY

gan BOLOGA, Cristian G., URSU, Oleg, HALIP, Liliana, CURPĂN, Ramona, OPREA, Tudor I.
Cyhoeddwyd yn Rev Roum Chim (2015)

Emerging Trends in the Discovery of Natural Product Antibacterials

gan Bologa, Cristian G., Ursu, Oleg, Oprea, Tudor, Melançon, Charles E., Tegos, George P.
Cyhoeddwyd 2013

A High Throughput Phenotypic Screen of Cytotoxic T Lymphocyte Lytic Granule Exocytosis Reveals Candidate Immunosuppressants

gan Zhao, Ziyan, Haynes, Mark K., Ursu, Oleg, Edwards, Bruce S., Sklar, Larry A., Zweifach, Adam
Cyhoeddwyd yn J Biomol Screen (2014)

Identification of new GLUT2-selective inhibitors through in silico ligand screening and validation in eukaryotic expression systems

gan Schmidl, Sina, Ursu, Oleg, Iancu, Cristina V., Oreb, Mislav, Oprea, Tudor I., Choe, Jun-yong
Cyhoeddwyd yn Sci Rep (2021)

A Chemogenomic Analysis of Ionization Constants - Implications for Drug Discovery

gan Manallack, David T., Prankerd, Richard J., Nassta, Gemma C., Ursu, Oleg, Oprea, Tudor I., Chalmers, David K.
Cyhoeddwyd 2013

Protein Biomarker Druggability Profiling

gan Mani, Subramani, Cannon, Daniel, Ohls, Robin, Oprea, Tudor, Mathias, Stephen, Ballard, Karri, Ursu, Oleg, Bologa, Cristian
Cyhoeddwyd yn J Biomed Inform (2017)

A high throughput flow cytometric assay platform targeting transporter inhibition

gan Tegos, George P., Evangelisti, Annette M., Strouse, J. Jacob, Ursu, Oleg, Bologa, Cristian G., Sklar, Larry A.
Cyhoeddwyd 2014

Badapple: promiscuity patterns from noisy evidence

gan Yang, Jeremy J., Ursu, Oleg, Lipinski, Christopher A., Sklar, Larry A., Oprea, Tudor I., Bologa, Cristian G.
Cyhoeddwyd yn J Cheminform (2016)

Discovery of a specific inhibitor of human GLUT5 by virtual screening and in vitro transport evaluation

gan George Thompson, Alayna M., Ursu, Oleg, Babkin, Petr, Iancu, Cristina V., Whang, Alex, Oprea, Tudor I., Choe, Jun-yong
Cyhoeddwyd yn Sci Rep (2016)

The CARLSBAD Database: A Confederated Database of Chemical Bioactivities

gan Mathias, Stephen L., Hines-Kay, Jarrett, Yang, Jeremy J., Zahoransky-Kohalmi, Gergely, Bologa, Cristian G., Ursu, Oleg, Oprea, Tudor I.
Cyhoeddwyd 2013

DrugCentral: online drug compendium

gan Ursu, Oleg, Holmes, Jayme, Knockel, Jeffrey, Bologa, Cristian G., Yang, Jeremy J., Mathias, Stephen L., Nelson, Stuart J., Oprea, Tudor I.
Cyhoeddwyd yn Nucleic Acids Res (2017)

High-Throughput Screening Approach for Identifying Compounds that Inhibit Non-Homologous End Joining

gan Bredemeyer, Andrea, Edwards, Bruce S., Haynes, Mark K., Morales, Abigail J., Wang, Yinan, Ursu, Oleg, Waller, Anna, Sklar, Larry A., Sleckman, Barry P.
Cyhoeddwyd yn SLAS Discov (2017)

DrugCentral 2018: an update

gan Ursu, Oleg, Holmes, Jayme, Bologa, Cristian G, Yang, Jeremy J, Mathias, Stephen L, Stathias, Vasileios, Nguyen, Dac-Trung, Schürer, Stephan, Oprea, Tudor
Cyhoeddwyd yn Nucleic Acids Res (2019)

Associating Drugs, Targets and Clinical Outcomes into an Integrated Network Affords a New Platform for Computer-Aided Drug Repurposing

gan Oprea, Tudor I., Nielsen, Sonny Kim, Ursu, Oleg, Yang, Jeremy J., Taboureau, Olivier, Mathias, Stephen L., Kouskoumvekaki, lrene, Sklar, Larry A., Bologa, Cristian G.
Cyhoeddwyd 2011

Conformational mAb as a Tool for Integrin Ligand Discovery

gan Njus, Ben H., Chigaev, Alexandre, Waller, Anna, Wlodek, Danuta, Ostopovici-Halip, Liliana, Ursu, Oleg, Wang, Wei, Oprea, Tudor I., Bologa, Cristian G., Sklar, Larry A.
Cyhoeddwyd 2009

Formalizing drug indications on the road to therapeutic intent

gan Nelson, Stuart J, Oprea, Tudor I, Ursu, Oleg, Bologa, Cristian G, Zaveri, Amrapali, Holmes, Jayme, Yang, Jeremy J, Mathias, Stephen L, Mani, Subramani, Tuttle, Mark S, Dumontier, Michel
Cyhoeddwyd yn J Am Med Inform Assoc (2017)

A comprehensive map of molecular drug targets

gan Santos, Rita, Ursu, Oleg, Gaulton, Anna, Bento, A. Patrícia, Donadi, Ramesh S., Bologa, Cristian G., Karlsson, Anneli, Al-Lazikani, Bissan, Hersey, Anne, Oprea, Tudor I., Overington, John P.
Cyhoeddwyd yn Nat Rev Drug Discov (2016)