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A comprehensive map of molecular drug targets

The success of mechanism-based drug discovery depends on the definition of the drug target. This definition becomes even more important as we try to link drug response to genetic variation, understand stratified clinical efficacy and safety, rationalize the differences between drugs in the same ther...

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Detalhes bibliográficos
Publicado no:Nat Rev Drug Discov
Main Authors: Santos, Rita, Ursu, Oleg, Gaulton, Anna, Bento, A. Patrícia, Donadi, Ramesh S., Bologa, Cristian G., Karlsson, Anneli, Al-Lazikani, Bissan, Hersey, Anne, Oprea, Tudor I., Overington, John P.
Formato: Artigo
Idioma:Inglês
Publicado em: 2016
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314433/
https://ncbi.nlm.nih.gov/pubmed/27910877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd.2016.230
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