A comprehensive map of molecular drug targets

The success of mechanism-based drug discovery depends on the definition of the drug target. This definition becomes even more important as we try to link drug response to genetic variation, understand stratified clinical efficacy and safety, rationalize the differences between drugs in the same ther...

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Pubblicato in:Nat Rev Drug Discov
Autori principali: Santos, Rita, Ursu, Oleg, Gaulton, Anna, Bento, A. Patrícia, Donadi, Ramesh S., Bologa, Cristian G., Karlsson, Anneli, Al-Lazikani, Bissan, Hersey, Anne, Oprea, Tudor I., Overington, John P.
Natura: Artigo
Lingua:Inglês
Pubblicazione: 2016
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Article
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC6314433/
https://ncbi.nlm.nih.gov/pubmed/27910877
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nrd.2016.230
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