Combining multiple structure and sequence alignments to improve sequence detection and alignment: Application to the SH2 domains of Janus kinases

Por Al-Lazikani, Bissan, Sheinerman, Felix B., Honig, Barry
Publicado em 2001

Blocking the survival of the nastiest by HSP90 inhibition

Por Workman, Paul, Clarke, Paul A., Al-Lazikani, Bissan
Publicado no Oncotarget (2016)

Distinctive Behaviors of Druggable Proteins in Cellular Networks

Por Mitsopoulos, Costas, Schierz, Amanda C., Workman, Paul, Al-Lazikani, Bissan
Publicado no PLoS Comput Biol (2015)

canSAR: an integrated cancer public translational research and drug discovery resource

Por Halling-Brown, Mark D., Bulusu, Krishna C., Patel, Mishal, Tym, Joe E., Al-Lazikani, Bissan
Publicado em 2012

canSAR: updated cancer research and drug discovery knowledgebase

Por Bulusu, Krishna C., Tym, Joseph E., Coker, Elizabeth A., Schierz, Amanda C., Al-Lazikani, Bissan
Publicado em 2014

canSAR: an updated cancer research and drug discovery knowledgebase

Por Tym, Joseph E., Mitsopoulos, Costas, Coker, Elizabeth A., Razaz, Parisa, Schierz, Amanda C., Antolin, Albert A., Al-Lazikani, Bissan
Publicado no Nucleic Acids Res (2016)

JARID2 is a direct target of the PAX3-FOXO1 fusion protein and inhibits myogenic differentiation of rhabdomyosarcoma cells

Por Walters, Zoë S, Villarejo-Balcells, Barbara, Olmos, David, Buist, Thomas WS, Missiaglia, Edoardo, Allen, Rebecca, Al-Lazikani, Bissan, Garrett, Michelle D, Blagg, Julian, Shipley, Janet
Publicado em 2013

Effective function annotation through catalytic residue conservation

Por George, Richard A., Spriggs, Ruth V., Bartlett, Gail J., Gutteridge, Alex, MacArthur, Malcolm W., Porter, Craig T., Al-Lazikani, Bissan, Thornton, Janet M., Swindells, Mark B.
Publicado em 2005

ChEMBL: a large-scale bioactivity database for drug discovery

Por Gaulton, Anna, Bellis, Louisa J., Bento, A. Patricia, Chambers, Jon, Davies, Mark, Hersey, Anne, Light, Yvonne, McGlinchey, Shaun, Michalovich, David, Al-Lazikani, Bissan, Overington, John P.
Publicado em 2012

Large-Scale Profiling of Kinase Dependencies in Cancer Cell Lines

Por Campbell, James, Ryan, Colm J., Brough, Rachel, Bajrami, Ilirjana, Pemberton, Helen N., Chong, Irene Y., Costa-Cabral, Sara, Frankum, Jessica, Gulati, Aditi, Holme, Harriet, Miller, Rowan, Postel-Vinay, Sophie, Rafiq, Rumana, Wei, Wenbin, Williamson, Chris T., Quigley, David A., Tym, Joe, Al-Lazikani, Bissan, Fenton, Timothy, Natrajan, Rachael, Strauss, Sandra J., Ashworth, Alan, Lord, Christopher J.
Publicado no Cell Rep (2016)

A HIF-regulated VHL-PTP1B-Src signaling axis identifies a therapeutic target in Renal Cell Carcinoma

Por Suwaki, Natsuko, Vanhecke, Elsa, Atkins, Katelyn M., Graf, Manuela, Swabey, Katherine, Huang, Paul, Schraml, Peter, Moch, Holger, Cassidy, Amy, Brewer, Daniel, Al-Lazikani, Bissan, Workman, Paul, De-Bono, Johann, Kaye, Stan B., Larkin, James, Gore, Martin. E., Sawyers, Charles L., Nelson, Peter, Beer, Tomasz M., Geng, Hao, Gao, Lina, Qian, David Z., Alumkal, Joshi J., Thomas, Gary, Thomas, George V.
Publicado em 2011

Genomic-scale prioritization of drug targets: the TDR Targets database

Por Agüero, Fernán, Al-Lazikani, Bissan, Aslett, Martin, Berriman, Matthew, Buckner, Frederick S., Campbell, Robert K., Carmona, Santiago, Carruthers, Ian M., Chan, A. W. Edith, Chen, Feng, Crowther, Gregory J., Doyle, Maria A., Hertz-Fowler, Christiane, Hopkins, Andrew L., McAllister, Gregg, Nwaka, Solomon, Overington, John P., Pain, Arnab, Paolini, Gaia V., Pieper, Ursula, Ralph, Stuart A., Riechers, Aaron, Roos, David S., Sali, Andrej, Shanmugam, Dhanasekaran, Suzuki, Takashi, Voorhis, Wesley C. Van, Verlinde, Christophe L. M. J.
Publicado em 2008

The genome of the blood fluke Schistosoma mansoni

Por Berriman, Matthew, Haas, Brian J., LoVerde, Philip T., Wilson, R. Alan, Dillon, Gary P., Cerqueira, Gustavo C., Mashiyama, Susan T., Al-Lazikani, Bissan, Andrade, Luiza F., Ashton, Peter D., Aslett, Martin A., Bartholomeu, Daniella C., Blandin, Gaelle, Caffrey, Conor R., Coghlan, Avril, Coulson, Richard, Day, Tim A., Delcher, Art, DeMarco, Ricardo, Djikeng, Appoliniare, Eyre, Tina, Gamble, John A., Ghedin, Elodie, Gu, Yong, Hertz-Fowler, Christiane, Hirai, Hirohisha, Hirai, Yuriko, Houston, Robin, Ivens, Alasdair, Johnston, David A., Lacerda, Daniela, Macedo, Camila D., McVeigh, Paul, Ning, Zemin, Oliveira, Guilherme, Overington, John P., Parkhill, Julian, Pertea, Mihaela, Pierce, Raymond J., Protasio, Anna V., Quail, Michael A., Rajandream, Marie-Adèle, Rogers, Jane, Sajid, Mohammed, Salzberg, Steven L., Stanke, Mario, Tivey, Adrian R., White, Owen, Williams, David L., Wortman, Jennifer, Wu, Wenjie, Zamanian, Mostafa, Zerlotini, Adhemar, Fraser-Liggett, Claire M., Barrell, Barclay G., El-Sayed, Najib M.
Publicado em 2009