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Distinctive Behaviors of Druggable Proteins in Cellular Networks

The interaction environment of a protein in a cellular network is important in defining the role that the protein plays in the system as a whole, and thus its potential suitability as a drug target. Despite the importance of the network environment, it is neglected during target selection for drug d...

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Detalhes bibliográficos
Publicado no:PLoS Comput Biol
Main Authors: Mitsopoulos, Costas, Schierz, Amanda C., Workman, Paul, Al-Lazikani, Bissan
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2015
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4689399/
https://ncbi.nlm.nih.gov/pubmed/26699810
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pcbi.1004597
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