Effective function annotation through catalytic residue conservation

Because of the extreme impact of genome sequencing projects, protein sequences without accompanying experimental data now dominate public databases. Homology searches, by providing an opportunity to transfer functional information between related proteins, have become the de facto way to address thi...

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Detalhes bibliográficos
Main Authors: George, Richard A., Spriggs, Ruth V., Bartlett, Gail J., Gutteridge, Alex, MacArthur, Malcolm W., Porter, Craig T., Al-Lazikani, Bissan, Thornton, Janet M., Swindells, Mark B.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2005
Assuntos:
Biological Sciences
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1178014/
https://ncbi.nlm.nih.gov/pubmed/16037208
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0504833102
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