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A global analysis of function and conservation of catalytic residues in enzymes

The catalytic residues of an enzyme comprise the amino acids located in the active center responsible for accelerating the enzyme-catalyzed reaction. These residues lower the activation energy of reactions by performing several catalytic functions. Decades of enzymology research has established gene...

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Detalles Bibliográficos
Publicado en:J Biol Chem
Main Authors: Ribeiro, António J. M., Tyzack, Jonathan D., Borkakoti, Neera, Holliday, Gemma L., Thornton, Janet M.
Formato: Artigo
Idioma:Inglês
Publicado: American Society for Biochemistry and Molecular Biology 2020
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6956550/
https://ncbi.nlm.nih.gov/pubmed/31796628
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.REV119.006289
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